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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L2
All Species:
5.15
Human Site:
S463
Identified Species:
16.19
UniProt:
Q9H6S3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6S3
NP_073609.2
715
80621
S463
I
R
N
S
Q
K
H
S
P
T
S
E
P
T
P
Chimpanzee
Pan troglodytes
XP_512904
745
82543
A494
Q
Q
S
A
P
Q
V
A
V
N
G
H
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001116697
615
68955
D392
V
N
T
C
G
G
P
D
I
A
R
S
V
S
C
Dog
Lupus familis
XP_534881
791
88639
P471
N
N
M
Y
T
R
G
P
Q
L
D
Q
G
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99K30
729
82211
S466
V
R
H
S
P
K
H
S
L
S
S
E
S
Q
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510664
556
62861
D333
L
L
T
R
S
A
I
D
L
L
Q
E
C
L
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
P451
F
F
G
S
Q
S
S
P
S
S
N
G
S
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
S699
G
Y
H
Q
R
Q
S
S
D
S
L
G
H
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
79.7
42.5
N.A.
84
N.A.
N.A.
29
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
58.2
80.8
60.1
N.A.
90.1
N.A.
N.A.
46.1
N.A.
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
0
0
0
N.A.
46.6
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
13.3
13.3
N.A.
66.6
N.A.
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
0
13
0
13
0
0
0
0
25
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
13
0
13
% C
% Asp:
0
0
0
0
0
0
0
25
13
0
13
0
0
13
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
38
0
13
0
% E
% Phe:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
13
0
13
13
13
0
0
0
13
25
13
0
0
% G
% His:
0
0
25
0
0
0
25
0
0
0
0
13
13
0
0
% H
% Ile:
13
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
13
0
0
0
0
0
0
25
25
13
0
0
13
13
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
25
13
0
0
0
0
0
0
13
13
0
0
0
13
% N
% Pro:
0
0
0
0
25
0
13
25
13
0
0
0
13
0
38
% P
% Gln:
13
13
0
13
25
25
0
0
13
0
13
13
13
13
0
% Q
% Arg:
0
25
0
13
13
13
0
0
0
0
13
0
0
0
0
% R
% Ser:
0
0
13
38
13
13
25
38
13
38
25
13
25
25
0
% S
% Thr:
0
0
25
0
13
0
0
0
0
13
0
0
0
13
0
% T
% Val:
25
0
0
0
0
0
13
0
13
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
13
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _